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Stroke

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A stroke occurs when there has been a sudden interruption of blood supply to an area of the brain. This can occur when a blood clot forms in an artery, occluding that artery thereby depriving that area of its blood supply. An embolism can have the same affect.

An embolism is either a 'travelling clot of blood', an air bubble or a fragment of tissue which travels through the blood stream. It will deprive an area of its blood when it becomes lodged in an artery. Rupture of the actual blood vessel can cause a local haemorrhage with the same effect.

Stroke is one of the major causes of death worldwide; it is the third most common cause in the UK. The incidence rises steeply with age and is uncommon under the age of 40 years. There are degrees of stroke. A minor stroke is one in which recovery of the patient occurs within a 24 hour period leaving no neurological defit.

A Transient Ischaemic Attack (TIA) is a focal deficit lasting less than 24 hours, following which there is a full recovery. Unfortunately, these attacks can occur at any time. Secondary causes have to be considered. There may be an underlying abnormality which directly causes the circulatory problem causing the stroke. Into that category come "space occupying lesions", a tumour or abscess.

In young adults about one fifth of strokes are caused by a dissection (split in the wall) of a major artery as the result of trauma or manipulation of the neck. For those patients who suffer from Hypertension, Diabetes, Obesity and who smoke, their risk of developing a stroke is much greater than most.

The clinical features of a stroke are that the signs and symptoms occur in a few minutes and develop over a period of several hours. It is not possible to accurately determine the precise cause in that time. A cerebral haemorrhage is, however accompanied by a severe headache. The situation of the haemorrhage can be localised as the part affected will indicate the area of the brain in which the "accident" took place.

The main purpose of the investigation is to differentiate between haemorrhage and infarction and to identify future (or present) risk factors which can be dealt with. CT or magnetic resonance imaging is indicated in most patients. This will demonstrate the site of the accident and give information as to whether it was haemorrhage or infarction and can possibly demonstrate any existing problem which could have precipitated the stroke. eg Neoplasm (Ca).
General investigations of blood and urine can also be of use in this line. eg. Clycosuvia (Diabetes), Raised Hb (Polycythermia), Raised ESR (Sedimentation rate - arteritis and vasculitis.

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