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Eye infections

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The eyes are exposed and are warm and moist: they are a perfect environment for microbes to grow. Eye infections can be potentially serious, leading to loss of visual clarity or even blindness.

Sites prone to infection:

(a) The conjunctiva (the delicate membrane stuck to the back of the eyelid which glides over the eye surface during blinking). Conjunctivitis is a very common infection caused by many organisms. It produces "pink-eye" and patients complain of a gritty sensation coupled with a slimy green discharge if the infection is bacterial and a watery discharge if it is viral. Hence, bacterial conjunctivitis tends to result in "sticky eye".

Two sexually transmitted diseases, gonorrhoea and chlamydia trachomatis can be passed onto babies by infected mothers at birth. Hence neonatal conjunctivitis should be properly investigated as these infections are more serious. Chlamydia trachomatis is the most important eye infection worldwide and by causing trachoma, 20 million are blinded by it in the world today. Transmission in the developing world is by contaminated flies, fingers and towels more than just during birth. It is associated with poor hygeine, overcrowding and an overabundant fly population.

Direct infection of the conjunctiva and cornea are possible through poor contact lens hygiene, or by excessive wearing reducing the eye's natural defence mechanisms. Many organisms can multiply within contact lens solution bottles, unchanged cleaning fluids and contaminated lenses.

(b) The cornea can be infected to produce keratitis. Viruses, bacteria, funghi and protozoa can all cause keratitis. In the Southern hemisphere, funghi are the commonest cause whereas bacteria are in the Northern Hemisphere. The condition is precipitated by contact lens wearing or injury to the eye from trauma or surgery. An abscess may well develop and then an ulcer. Keratitis is very serious as the cornea can rupture needing transplant or leading to blindness.

(c) The anterior chamber can be infected to produce intraocular endophthalmitis. Again this is very serious and without prompt diagnosis and treatment, surgical removal of the eye will be needed. It results from surgery such as cataract removal and hence pre-operative antibiotic eye-drops are used to destroy the natural bacteria around the eye.

(d) Orbital cellulitis is caused by blood-borne spread to the tissues around the eye itself. There is red, painful swelling around the eye usually caused by bacteria.

(e) If the retina and choroid are infected, retinochoroiditis is diagnosed. Unlike the rest of the eye, the retina and choroid have a rich blood supply that can result in blood-borne retinochoroiditis. Parasites are a common cause, as is CMV virus in AIDS patients. Infamously difficult to treat, retinochoroiditis can result in blindness. Toxoplasmosis can also affect this area; an infection acquired from infected cat and dog faeces. ..

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