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Cystic fibrosis

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This condition has an incidence of one in every 2000 live births has a genetic cause. A faulty gene causes an inability to transport salt in particular types of cells in the lungs and pancreas. Symptoms result from a widespread dysfunction of the exocrine glands with damage to the pancreas and lungs due to blockages of their ducts with sticky, tenacious secretions. It is characterised by repeated chest infections, pneumonia and other breathing problems. The pancreatic disorder causes malabsorption, particularly of fat and this nutrient may pass through the body resulting in weight loss and pale fatty stools (steatorrhoea). This may also mean if suitable measures are not taken, the patient becomes deficient in fat-soluble vitamins and fatty acids. Malnutrition and poor growth are common features of this disease. The sweat of cystic fibrosis patients contains an increased amount of salt. This coupled with diarrhoea may sometimes lead to sodium deficiency.

When the digestive system is involved, just after birth, the bowels may not operate and cause obstruction of the bowel content.

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