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Ulcerative Colitis

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Ulcerative Colitis is an inflammatory bowel disease, which presents itself in one in 1000 people in the Western world. Symptoms include diarrhoea, which may contain pus, blood or mucus, with or without stomach pains. There may be weight loss, weakness, fever and general malaise. The condition results from the ulceration and bleeding of the large intestine and manifests itself as acute attacks interspersed with spells of remission. In severe episodes up to twenty stools can be passed per day and frequent diarrhoea and bleeding can result in electrolyte imbalances and anaemia, respectively.

Other complications include, malnutrition, perforation of the bowel (in rare cases), inflammation of the skin, joints and eyes and after ten years an increased risk of bowel cancer.

In its active form ulcerative colitis may be treated with drugs such as sulphasalazine and corticosteroids. Iron supplements may be required if anaemia occurs. In more severe attacks, electrolyte imbalance may need to be restored and in some instances blood transfusions may be indicated. When medication fails, surgical intervention may be required to remove part or all of the large bowel. A protocolectomy with a permanent ileostomy is the standard type of surgery for patients with this disease.

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