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Risk factors

 
 

Overview

There is generally no single cause of cancer. Chromosome damage and inherited or acquired defects in the immune system can play a part. Ageing leads to a weakening of the immune system, and climate and cultural practice can also influence incidence. Diagnosis of cancer in people who have become bereaved in the previous 18 months or so is also common, suggesting a possible emotional element.

Early Warnings of Cancer
Most infections clear up in time but cancer does not. Consult your doctor if you have any of these symptoms:

  • sores that don't heal
  • unexplained swelling
  • persistent indigestion or a change in bowel habits unrelated to diet. If you become aware of a lump or swelling in the abdominal area
  • unexplained weight loss of more than 0.5 kg (1lb) a week
  • increasing difficulty passing urine
  • hoarseness lasting more than a month
  • unusual bleeding from mouth, anus, genitals or nipples
  • a mole or wart that starts to bleed, gets bigger or changes colour
  • a persistent lump or thickening anywhere on the skin
  • blood stained sputum; particularly if you smoke

Meat consumption and cancer risk
Eating red and processed meats has been linked with higher risk of bowel cancer and possibly breast and prostate cancers. One theory is that cooking meat at high temperatures produces compounds called heterocyclic amines (HCAs), which are powerful cancer-causing agents in animals. It is likely they have a similar effect in humans. Also, polycyclic aromatic hydrocarbons (PAHs) are formed when the fat in food drips on a flame, heating element or hot coals. These carcinogenic chemicals waft up in smoke and can land on food, or form directly on food when it's cooked to a crisp.

Then there's fat. Red meat is a major source of saturated fat, which has been linked with higher risk of cancers of the lung, colon, rectum, breast, uterus and prostate. Poultry has not shown an association with cancer in most studies. Fish can form HCAs but it also contains omega-3 fatty acids, which are associated with reduced cancer risk. Consumption of red and processed meats should therefore be moderate to zero.

The general emphasis should perhaps be on making meat less of a focus for most meals and more of an accompaniment to vegetable and grain dishes.

Added Risk from Obesity
Obesity can be implicated directly in the respect that if you are overweight the physcial detection of a lump can be that much more difficult, particularly in the breast and abdominal regions.

Obese people tend to be less physically active, so cancer risk may well be increased. It is, therefore, important to keep weight down through healthy eating and sensible exercise. Consult a doctor if necessary.

High fat, high risk
High fat diets can enhance colon cancer risk. Recommendations to cut total fat intake to 30% of energy and to increase Omega 3 fatty acid consumption in order to reduce risk of cardiovascular disease might also help reduce bowel cancer rates. Whatever doubts there might be about a direct link between fats and breast cancer, low-fat diets in general help reduce obesity, which is itself a cancer risk, as we have seen above.

Psychological stress and cancer - could they be related?
Some scientists have argued that there is a link between psychological stress and cancer. Various studies have shown an increased incidence of early death, including cancer death, among people who have recently lost a spouse or loved one. However, most cancers have been developing over many years and are diagnosed only after they have been growing in the body for a long time (from two to three years). This would appear to argue against a link between a stressful event and cancer. But it is known that many types of stress activate the body's endocrine (hormone) system, which can cause changes in the immune system - the body's defence against infection and disease - including cancer. This is a 'grey' area and leads to much speculation.

The immune system is a highly specialised network that is affected by many factors. So far it has not been shown that stress-induced changes in the system directly cause cancer. Still, the link between breast cancer and stress has been studied extensively. Some research has pointed to higher rates of breast cancer among women who experienced traumatic life events and losses several years before diagnosis but a direct cause and effect is extremely hard to prove. It is worth remembering that stress reduction is of benefit for many other health reasons.

Can alcohol cause cancer?

There is no evidence to support the theory that alcohol causes cancer. But too much alcohol has so many other bad effects on health that it is sensible not to drink too much.

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